Temperature-dependent ligand relocation reveals plasticity of TRPM4 inhibition
Dominic Schneiter, Jean‐Sébastien Rougier, Hugues Abriel, Henning Stahlberg, Babatunde Ekundayo
This study shows that the inhibitor PBA binds to TRPM4 in different locations at 8°C and 37°C, revealing temperature-dependent changes in ligand recognition.
bioRxiv · Jun 9, 2026 · PreprintBiophysics