Author
Vrije Universiteit BrusselORCID 0009-0002-1319-883XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Yingnan Lei, Nuša Krivec, Arkajyoti Sarkar…·Claudia Spits
This study shows that increased BCL2L1 and ID1 gene dosage in human pluripotent stem cells drives competitive advantage and fate bias toward non-neural ectodermal and extraembryonic fates during differentiation.
Yingnan Lei, Mai Chi Duong, Nuša Krivec…·Claudia Spits
This study shows that loss of chromosome 18q in hESCs impairs differentiation into retinal progenitor cells by disrupting TGFβ signaling and anteroposterior neuroectodermal fate commitment.
Marius Regin, Yingnan Lei, Edouard Couvreu de Deckersberg…·Claudia Spits
The paper investigates the cellular consequences of aneuploidy in human blastocysts, finding p53-mediated apoptosis and impaired lineage segregation.
Diana Al Delbany, Manjusha S. Ghosh, Nuša Krivec…·Claudia Spits
This study tracks genetic changes in human pluripotent stem cells over time, finding that recurrent chromosomal gains drive the accumulation of other mutations.