Author

John M. Pum

University of MinnesotaORCID 0009-0002-1462-0094Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

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Aaron C. GoldstrohmiD· 1 shared Carmen Hernandez-PereziD· 1 shared Elise B. DunsheeiD· 1 shared Katherine M. McKenneyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperMolecular Biology

Aaron C. GoldstrohmORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 2, 2025

Cytoplasmic poly-adenosine binding proteins modulate susceptibility of mRNAs to RNA-binding protein-directed decay

Katherine M. McKenney, Carmen Hernandez-Perez, Elise B. Dunshee…·Aaron C. Goldstrohm

This study shows that PABPCs modulate PUM1/2-mediated mRNA decay by protecting poly(A) tails, with PABPC levels determining mRNA susceptibility to degradation.

DOI 10.1101/2025.10.02.680050

humanexperimental assay

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