Author
University of MinnesotaORCID 0000-0003-1607-7646Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Katherine M. McKenney, Mika Nevo, Robert P. Connacher…·Aaron C. Goldstrohm
The paper identifies the regulatory roles of the CCR4-NOT complex in mRNA deadenylation and decay by analyzing transcriptome-wide effects of subunit depletion.
Elise B. Dunshee, Brenna A Saladin, David J. Turner…·Aaron C. Goldstrohm
The paper identifies how human PUM proteins repress mRNAs by using fuzzy multivalent hydrophobic interactions to recruit the CCR4-NOT deadenylase complex through their intrinsically disordered RD3 domain.
Katherine M. McKenney, Carmen Hernandez-Perez, Elise B. Dunshee…·Aaron C. Goldstrohm
This study shows that PABPCs modulate PUM1/2-mediated mRNA decay by protecting poly(A) tails, with PABPC levels determining mRNA susceptibility to degradation.
Katherine M. McKenney, Robert P. Connacher, Elise B. Dunshee, Aaron C. Goldstrohm
The paper introduces Chemi-Northern, a chemiluminescent northern blot method for RNA detection and quantitation, showing it is sensitive, fast, and suitable for analyzing natural and engineered RNAs.