ImmunologyPLoS PathogensPeer-reviewed
NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni
Madhusoodhanan Suresh Kumar Meena Kumari, Pengyu Liu, Megan Susanne Nitchman…·Parisa Kalantari
This study identifies NLRP3 and AIM2 inflammasomes as key drivers of pathogenic Th17 responses in Schistosoma mansoni infection, showing their role in promoting inflammation and their counteraction by the IFN-I pathway.
8 citations