Anne Goupil-Lamy

This study investigates how the R39C mutation in sialin affects its lysosomal transport function by analyzing structural and dynamic changes in the protein.

The paper challenges the conventional view of GPCR internalization by showing multiple pathways regulate receptor internalization, with specific findings on the GLP-1R's mechanism.

This study evaluates AlphaFold3 and AlphaFold2-Multimer for nanobody epitope prediction, finding overall success rates below 50% and highlighting CDR3 characteristics as key factors affecting accuracy.