Luke Drake

Granule cells reorient cortical trajectories to separate contexts

In mice learning two tasks, cerebellar granule cells kept the low-rank geometry of premotor cortical output within each task but rotated their population trajectories apart between tasks, while cortex generalized.

Predictive and instructive cerebellar encoding of dopamine reward drives motivated behavior

This study shows that cerebellar granule cells and climbing fibers encode dopamine rewards predictively and instructively, contributing to motivated behavior.