Mark J. Wagner

In mice learning two tasks, cerebellar granule cells kept the low-rank geometry of premotor cortical output within each task but rotated their population trajectories apart between tasks, while cortex generalized.

This study shows that cerebellar granule cells and climbing fibers encode dopamine rewards predictively and instructively, contributing to motivated behavior.

Connectome-seq maps neuronal connectivity at single-synapse resolution using barcoding and sequencing, revealing molecular markers in connected neurons.

The paper develops a general theory of cerebellum-like structures and their afferent pathways, predicting functional roles and reconciling existing theories.

This study investigates how birth timing influences the wiring and physiological response properties of cerebellar granule cells by comparing early- and late-born cells using viral tracing and in vivo imaging.

The paper shows that reciprocal repulsions between Teneurin-3 and Latrophilin-2 guide the assembly of parallel hippocampal networks during development.

EXTRACT, a GPU-based cell extraction method using one-sided Huber robust regression, processed 199 Allen Brain Observatory sessions (~12 TB) in a day and gave cleaner traces than CAIMAN or CNMF-E.

The paper uses time-lapse imaging in Drosophila to study how olfactory receptor neurons target axons to specific glomeruli, revealing dynamics of branching and bilateral interactions.

This study shows that GluD2 and Cbln1 mediate competitive synaptogenesis, shaping Purkinje cell dendritic arbors in the cerebellum through competitive synapse formation.

The paper examines how transcriptomic types of mouse prefrontal cortex projection neurons relate to axonal projections and encoding properties across cognitive tasks, finding redundant but quantitatively biased task signal encoding.