Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes
Jabia M. Chowdhury, Eduardo A. Chacin Ruiz, Matthew P. Ohr, Katelyn E. Swindle‐Reilly, Ashlee N. Ford Versypt
This study develops spatial models of rabbit and human vitreous to analyze bevacizumab distribution and elimination, showing anterior elimination dominates in rabbits and both anterior/posterior elimination are important in humans.
Journal of Pharmaceutical Sciences · Dec 16, 2024Peer-reviewedSystems Biology