Author

Ke-Wei Chen

Peking UniversityORCID 0009-0002-3579-240XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Cuizhen WangiD· 1 shared Hui-si Huang· 1 shared Jia-He Qiu· 1 shared Jian‐bo WangiD· 1 shared Jianan CheniD· 1 shared Kin Kuan HoiiD· 1 shared Tianyu SuniD· 1 shared Xing WuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Cuizhen WangORCID

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1 paper

Recent·Most cited

A De Novo Design Strategy to Convert FAcD from Dimer to Active Monomer

Ke-Wei Chen, Cuizhen Wang, Hui-si Huang, Xing Wu, Jianan Chen, Jia-He Qiu, Kin Kuan Hoi, Tianyu Sun, Jian‐bo Wang, Yun‐Dong Wu

This paper presents a de novo design strategy to convert the dimeric enzyme FAcD into an active monomer, achieving high catalytic activity with a mutant showing improved thermal stability.

bioRxiv · Jan 11, 2025 · PreprintBioengineering