GeneticsHuman Molecular GeneticsPeer-reviewed
Association of Whole-Person Eigen-Polygenic Risk Scores with Alzheimer's Disease
Amin Kharaghani, Earvin S. Tio, Milos S. Milic…·Daniel Felsky
The paper develops eigen-polygenic risk scores (ePRSs) from clustered subnetworks of single-trait PRSs and shows they improve prediction of Alzheimer's Disease and related phenotypes.