Zhiyong He

The paper uses long-read sequencing to characterize lentiviral provirus insertions in clonal CAR-T cell lines, revealing structural variations missed by short-read and ddPCR methods.

This paper presents near-complete, haplotype-resolved assemblies of a pancreatic cancer genome and normal tissue, identifying extensive somatic variants and epigenetic changes in previously excluded regions.

The paper describes a comprehensive genomic dataset from a tumor-normal pair with broad consent, generated using multiple sequencing technologies for benchmarking somatic variant detection.