Author

Clay Shyu

University of British ColumbiaORCID 0009-0002-5989-8380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeremy R. Nan· 1 shared Luke McAlaryiD· 1 shared Mine Sher· 1 shared Neil R. CashmaniD· 1 shared Steven Samuel PlotkiniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Jeremy R. Nan

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1 paper

Recent·Most cited

Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells

Luke McAlary, Jeremy R. Nan, Clay Shyu, Mine Sher, Steven Samuel Plotkin, Neil R. Cashman

The paper identifies amyloidogenic regions in beta-strands II and III of SOD1 that modulate aggregation and toxicity in ALS mutants, showing that proline mutations reduce these effects.

Open Biology · Jun 1, 2024Peer-reviewedMolecular Biology