Molecular BiologyOpen BiologyPeer-reviewed
Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells
Luke McAlary, Jeremy R. Nan, Clay Shyu…·Neil R. Cashman
The paper identifies amyloidogenic regions in beta-strands II and III of SOD1 that modulate aggregation and toxicity in ALS mutants, showing that proline mutations reduce these effects.
4 citations