Simultaneous ligand binding to intact and partially formed ATP binding sites in the hexameric termination factor Rho
Tyler D Billings, Kristie Baker, Philip Lacey, Matthew J. Benedek, Rodrigo Muzquiz, Vicki Hopper Wysocki, Mark P. Foster
The paper uses native mass spectrometry to study ATP binding to Rho, revealing binding to hexameric and lower-order complexes and super-stoichiometric binding at partially formed sites.
Journal of Biological Chemistry · Oct 9, 2025Peer-reviewedBiophysics