Author

Lingfeng Shi

University of TorontoORCID 0009-0002-6696-8842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2 Approach:contrastive learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Han ZhouiD· 2 shared Daoyun DingiD· 1 shared Dehan Li· 1 shared Yang Lu· 1 shared Yang Young LuiD· 1 shared Yifan YangiD· 1 shared Yifan Yang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBioinformatics

Han ZhouORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 4, 2026

Error-Controlled Discovery of Protein Interactions via Conformal Calibration

Yifan Yang, Dehan Li, Daoyun Ding…·Yang Young Lu

PPI-Caliper controls false discovery rate in protein interaction prediction using conformal calibration without retraining models.

DOI 10.64898/2026.11.03.764142

protein sequencecontrastive learning

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 4, 2026

Representation-aware calibration enables statistically reliable protein structure search

Lingfeng Shi, Han Zhou, Yifan Yang, Yang Lu

Struct-Caliper improves protein structure search reliability by providing accurate p-values, increasing homolog recovery and reducing false discoveries compared to native E-values.

DOI 10.64898/2026.11.03.764110

protein structurestatistical model

𝕏 PostBluesky