Cyclodextrin-Based Delivery of the Annexin A1 Mimetic Peptide Ac2-26 Enhances Anti-Inflammatory Effects and PreventsDengue-Induced Lethality in Combination with AntiviralTherapy
Jenniffer Ramos Martins, Viviane Lima Batista, Laís Gomes Ramos, Celso Martins Queiroz‐Junior, Talita Cristina Martins da Fonseca, Angélica Samer Lallo Dias, LUISA CONY AYRES DE MIRANDA PEREIRA SALUSTIANO DA SILVA, Felipe Rocha da Silva Santos, Ana Luiza de Castro Santos, Ivana Silva Lula, Felipe Emanuel Oliveira Rocha, Jéssica Aparecida Barsalini Pereira, Edvaldo Souza Lara, Thiago Moreno L. Souza, Lirlandia Pires Sousa, , Vivian Vasconcelos Costa
This study shows that cyclodextrin-based delivery of the anti-inflammatory peptide Ac2-26 improves survival in dengue-infected mice when combined with antiviral therapy.
bioRxiv · Sep 2, 2025 · PreprintImmunology