BiochemistryJournal of Biological ChemistryPeer-reviewed
Probing the structural heterogeneity of Pup ligase PafA using H/D exchange mass spectrometry
Alicia Plourde, Jacquelyn C. Ogata-Bean, Siavash Vahidi
This study uses HDX-MS to investigate the oligomeric states and conformational dynamics of PafA, revealing its monomeric and dimeric forms and how nucleotide binding affects its structure and function.