Cancer BiologybioRxivPreprint
Pharmacological inhibition of LIN28A promotes imatinib sensitivity in CML resistance
Owen F.J. Hovey, Alyssa Wu, Tingting Wu…·Shawn Li
This study shows that inhibiting LIN28A with LIN28i-1632 enhances imatinib sensitivity in imatinib-resistant CML cells by reducing BCR-ABL abundance and disrupting the AKT survival pathway.
DOI 10.64898/2026.04.27.720799