MicrobiologybioRxivPreprint
A metabolic checkpoint coordinates bacterial cell envelope biosynthesis and c-di-GMP signaling
Xuhui Zheng, Katayoun Daneshjoo, Angeli Shieh…·Matthew R. Parsek
This study shows that acetyl-CoA inhibits PDEs in Pseudomonas aeruginosa, linking cell envelope biosynthesis to c-di-GMP signaling and biofilm formation.
DOI 10.64898/2026.06.11.731730