Molecular BiologybioRxivPreprint
Loss of Ythdf3 causes Danon disease-like features
Cong Yu, Chenzhong Xu, Jie Zhang…·Baohua Liu
This study shows that loss of Ythdf3 in mice causes Danon disease-like features due to impaired Sox9 mRNA decay, and targeted therapy with AAV-shRNA against Sox9 improves disease outcomes.
DOI 10.1101/2025.06.10.658803