Author

Aurora D’Amato

University of Wisconsin SystemORCID 0009-0002-8940-0010Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

Alexa R. HeatoniD· 2 shared Melissa C. SkalaiD· 2 shared Samantha K. BurkardiD· 2 shared Alexander L. RakhmilevichiD· 1 shared Alina A. HamptoniD· 1 shared Amy K. ErbeiD· 1 shared Anna HoefgesiD· 1 shared Anqi GaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersCancer Biology

Alexa R. HeatonORCID

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2 papers

Recent·Most cited

Atovaquone-induced therapeutic rewiring of melanoma metabolism

Mayra A. Betancourt Ponce, Alexa R. Heaton, Samantha K. Burkard, Aurora D’Amato, Nicha Boonpattrawong, Melissa C. Skala, Manish S. Patankar, Lisa Marie Barroilhet

This study shows atovaquone inhibits OXPHOS and glycolysis in melanoma, causing metabolic reprogramming, oxidative stress, and reduced tumor growth in vitro and in vivo.

Journal of Investigative Dermatology · Mar 24, 2026Peer-reviewedCancer Biology

Divergent role of CD8 T cells with distinct metabolic phenotypes during curative radio-immunotherapy in hot versus cold tumors

Alexa R. Heaton, Nathaniel J. Burkard, Anqi Gao, Anna Hoefges, Arika S. Feils, Samantha K. Burkard, Mildred A. R. Felder, Noah W. Tsarovsky, Daniel V. Spiegelman, Garrett M. Lublin, Alina A. Hampton, Aurora D’Amato, Huy Q. Dinh, Alexander L. Rakhmilevich, Amy K. Erbe, , Melissa C. Skala

This study examines how CD8 T cells with different metabolic profiles contribute to tumor cure in hot versus cold murine tumors using radio-immunotherapy.

bioRxiv · Oct 24, 2025 · PreprintImmunology