Author

Arika S. Feils

University of Wisconsin–MadisonORCID 0000-0002-9349-4534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Amy K. ErbeiD· 5 shared Alexander L. RakhmilevichiD· 4 shared Alina A. HamptoniD· 4 shared Mildred A. R. Felder· 4 shared Noah W. TsarovskyiD· 4 shared Paul M. SondeliD· 4 shared Jen ZaborekiD· 3 shared Mackenzie Heck· 3 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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5 shared papersCancer Biology

Amy K. ErbeORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Bispecific GD2xB7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma

Amy K. Erbe, Arika S. Feils, Sabrina Reinthaler, Alina A. Hampton, Zachary T. Rosenkrans, Yadira Medina-Guevara, Mildred A. R. Felder, Jessica M. Wiwczar, Daniel Gerhardt, Mark R. Bercher, Belinda B. Wenke, Callie Haertle, Mackenzie Heck, Kaia Heimstreet, Elizabeth Frankel, , PaulM. Sondel

This paper describes a bispecific antibody that targets GD2 and B7-H3 to improve tumor targeting and reduce toxicity in neuroblastoma treatment.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Immune-mediated Engagement of T Regulatory Cells with Tumor Cells Results in Trogocytosis and Tumor Cell Killing.

Amy K. Erbe, Arika S. Feils, Anqi Gao, Sabrina N. VandenHeuvel, Simon Boyenga, Alina A. Hampton, Mackenzie Heck, Jen Zaborek, Daniel Spiegelman, Noah W. Tsarovsky, Anna Hoefges, Alexander A. Pieper, Peter M. Carlson, Mildred A. R. Felder, Ravi B. Patel, , Paul M. Sondel

The paper shows CD4 T regulatory cells can kill tumor cells through trogocytosis after immunocytokine treatment in a melanoma model.

bioRxiv · Dec 23, 2025 · PreprintCancer Biology

Divergent role of CD8 T cells with distinct metabolic phenotypes during curative radio-immunotherapy in hot versus cold tumors

Alexa R. Heaton, Nathaniel J. Burkard, Anqi Gao, Anna Hoefges, Arika S. Feils, Samantha K. Burkard, Mildred A. R. Felder, Noah W. Tsarovsky, Daniel V. Spiegelman, Garrett M. Lublin, Alina A. Hampton, Aurora D’Amato, Huy Q. Dinh, Alexander L. Rakhmilevich, Amy K. Erbe, , Melissa C. Skala

This study examines how CD8 T cells with different metabolic profiles contribute to tumor cure in hot versus cold murine tumors using radio-immunotherapy.

bioRxiv · Oct 24, 2025 · PreprintImmunology

Targeting both GD2 and B7-H3 using bispecific antibody improves tumor selectivity for GD2-positive tumors

Zachary T. Rosenkrans, Amy K. Erbe, Nathan B. Clemons, Arika S. Feils, Yadira Medina-Guevara, Justin J. Jeffery, Todd E. Barnhart, Jonathan W. Engle, Paul M. Sondel, Reinier T. Hernandez

This paper develops a bispecific antibody targeting GD2 and B7-H3 to improve tumor selectivity and reduce toxicity in GD2-positive tumors.

Bioconjugate Chemistry · Jul 31, 2025Peer-reviewedBioengineering

Bispecific GD2 x B7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma

Amy K. Erbe, Arika S. Feils, Alina A. Hampton, Zachary T. Rosenkrans, Mildred A. R. Felder, Jessica M. Wiwczar, Daniel J. Gerhardt, Mark R. Bercher, Belinda B. Wenke, Callie Haertle, Mackenzie Heck, Sabrina N. VandenHeuvel, Lizzie Frankel, Megan Nielsen, Dan Spiegelman, , Paul M. Sondel

bioRxiv · May 23, 2024 · PreprintCancer Biology