LRRC8A/D-containing anion channels mediate swelling-activated taurine release in the mouse brain
Michael J. Chandler, Julia W. Nalwalk, Preeti Dohare, Ariella D. Sprague, Alexandra L. Schober, Alexander A. Mongin
This study identifies LRRC8A/D-containing VRACs as the main pathway for swelling-activated taurine release in the brain but shows this pathway is not essential for systemic osmoregulation.
bioRxiv · Oct 23, 2026 · PreprintNeuroscience