Molecular BiologyMolecular Therapy AdvancesPeer-reviewed
Humanized mice enable in vivo evaluation of engineered plasma cell biology and therapeutic function
Tyler F. Hill, Anna E Helmers, Rene Yu-Hong Cheng…·Richard G. James
This study develops a humanized mouse model to evaluate engineered plasma cells and their therapeutic antibody secretion, showing long-term antibody production and neutralization of SARS-CoV-2.
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