Author

Tobias Schmelzle

Novartis Institutes for BioMedical ResearchORCID 0009-0003-1237-195XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Antoine de WeckiD· 1 shared Audrey KauffmanniD· 1 shared E. Robert McDonaldiD· 1 shared Éric BillyiD· 1 shared Hans BitteriD· 1 shared Javad Golji· 1 shared Joshua M. KorniD· 1 shared Michael D. JonesiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Antoine de WeckORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Correction of copy number induced false positives in CRISPR screens

Antoine de Weck, Javad Golji, Michael D. Jones, Joshua M. Korn, Éric Billy, E. Robert McDonald, Tobias Schmelzle, Hans Bitter, Audrey Kauffmann

The paper introduces two methods to correct false positives in CRISPR screens caused by copy number variations, reducing false positives by 70-80% in amplified regions.

PLoS Computational Biology · Jul 19, 2018Peer-reviewedBioinformatics