A bispecific antibody-drug conjugate targeting pCAD and CDH17 has antitumor activity and improved tumor specificity
Alyssa Synan, Nila C. Wu, Roberto Velazquez…·Joseph A. D’Alessio
This study develops a bispecific antibody-drug conjugate targeting pCAD and CDH17, showing antitumor activity in dual antigen-expressing tumors but not in single antigen-expressing tumors.