Author

Marissa Fujimoto

Fred Hutch Cancer CenterORCID 0009-0003-1288-7067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alice H. BergeriD· 1 shared Amy R. Lowe· 1 shared Siobhan O’BrieniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperGenetics

Alice H. BergerORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintSep 29, 2026

Transcriptional adaptation influences buffering among essential paralog gene families

Siobhan O’Brien, Marissa Fujimoto, Amy R. Lowe, Alice H. Berger

The paper investigates transcriptional adaptation in paralog gene families using Perturb-seq, finding six paralog pairs show adaptation and identifying mechanisms like nonsense-mediated decay and nuclear import.

DOI 10.64898/2026.09.24.754217

humanCRISPR screen

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