Author

Hana Bernhardova

Masaryk UniversityORCID 0009-0003-1797-9374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

David BednářiD· 1 shared Jiřı́ DamborskýiD· 1 shared Martin MarekiD· 1 shared Martin TouliD· 1 shared Ondřej VávraiD· 1 shared Sérgio M. MarquesiD· 1 shared Tadeja GaoiD· 1 shared Veronika Novakova· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

David BednářORCID

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintSep 17, 2025

Molecular trick to reverse SN2 mechanism in hydrolytic enzyme

Martin Toul, Sérgio M. Marques, Tadeja Gao…·Martin Marek

This paper shows that replacing histidine with phenylalanine in haloalkane dehalogenase reverses the SN2 mechanism by remodeling the active site, enabling reversible reactions for sustainable transhalogenation.

DOI 10.1101/2025.09.17.676745

experimental assayprotein folding & dynamics

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