An allelic series of spontaneous mutations in Rorb cause a gait phenotype, retinal abnormalities, and transcriptomic changes relevant to human neurodevelopmental conditions
George C Murray, Jason A. Bubier, Oraya J. Zinder, Belinda S. Harris, James Clark, Mia-Cara Christopher, Courtany Hanley, Harianto Tjong, Meihong Li, Chew Yee Ngan, Laura G. Reinholdt, Robert W. Burgess, Abby LD Tadenev
The paper describes five Rorb mutant mouse strains with gait and retinal abnormalities, showing transcriptomic changes linked to neurodevelopmental disorders.
bioRxiv · Nov 23, 2021 · PreprintGenetics