Oraya J. Zinder

Direct visualization of MCM helicase activation and replisome coupling in situ

This study uses MINFLUX nanoscopy to directly visualize MCM helicase activation and replisome coupling in human cells, showing sister replisomes remain coupled at ~40 nm during S phase.

An allelic series of spontaneous mutations in Rorb cause a gait phenotype, retinal abnormalities, and transcriptomic changes relevant to human neurodevelopmental conditions

The paper describes five Rorb mutant mouse strains with gait and retinal abnormalities, showing transcriptomic changes linked to neurodevelopmental disorders.

The genome of C57BL/6J \"Eve\", the mother of the laboratory mouse genome reference strain

The paper generates a new de novo genome assembly for C57BL/6J Eve, addressing genetic drift in the reference strain and improving genomic accuracy.