Harianto Tjong

This study shows ecDNA forms nuclear condensates and reorganizes chromatin to enhance oncogenic transcription across cancer types.

The paper describes five Rorb mutant mouse strains with gait and retinal abnormalities, showing transcriptomic changes linked to neurodevelopmental disorders.

ChIA-PIPE is a fully automated pipeline for analyzing and visualizing ChIA-PET data, including quality assessment and visualization tools.

This study uses nanopore sequencing to identify structural variants in breast cancer with high specificity and sensitivity, revealing repetitive DNA as a major source of variation.