Molecular BiologybioRxivPreprint
TRIB2 couples UCP1 degradation to thermogenic adaptation and metabolic health
Jiin-Horng Lee, Li-Yun Chueh, Sui-Chih Tien…·Yi‐Cheng Chang
This study identifies a TRIB2 variant linked to thermogenic capacity and shows that TRIB2 promotes UCP1 degradation, affecting metabolic health and obesity resistance.
DOI 10.1101/2025.10.26.684708