BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Basic interactions responsible for thymus function explain convoluted medulla shape
David Muramatsu, Henrik Weyer, Florian M. Gartner, Erwin Frey
This paper presents a theoretical model showing that signaling pathways between medullary stroma and thymocytes shape the medulla's convoluted structure and influence thymocyte negative selection.