Author

Amanda Tracz

Roswell Park Comprehensive Cancer CenterORCID 0009-0003-2335-7571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Anmbreen JamrozeiD· 1 shared Changmeng CaiiD· 1 shared Dean G. TangiD· 1 shared Gurkamal S. ChattaiD· 1 shared Han Yu· 1 shared Igor J. PuzanoviD· 1 shared Jason S. KirkiD· 1 shared Jiaoti HuangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anmbreen JamrozeORCID

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1 paper

Recent·Most cited

Cancer BiologySignal Transduction and Targeted TherapyPeer-reviewedMay 1, 2026

Cell-resolved high-dimensional imaging analysis, therapeutic modeling, and a Phase Ib clinical study validate BCL-2 as a target across heterogeneous CRPC subtypes

Anmbreen Jamroze, Xiaozhuo Liu, Surui Hou…·Dean G. Tang

This study validates BCL-2 as a therapeutic target in CRPC by showing its upregulation under AR inhibition and demonstrating efficacy of BCL-2 inhibitors in preclinical and clinical models.

1 citation

humanimaging

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