Author

David Fries

Purdue University West LafayetteORCID 0009-0003-3006-9180Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:statistical model· 1

Frequent Co-Authors

Geethma LirushieiD· 1 shared Hana HalliD· 1 shared Kendall Cottingham· 1 shared Nima GoodarziiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Geethma LirushieORCID

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1 paper

Recent·Most cited

Molecular BiologyFrontiers in Aging NeurosciencePeer-reviewedSep 14, 2026

Tau-induced elevation in promoter-proximal RNA polymerase II pausing is linked to decreased expression of long neuronal genes in a Drosophila tauopathy model.

Kendall Cottingham, Nima Goodarzi, David Fries…·Hana Hall

The paper investigates how pathological tau affects gene expression in a Drosophila tauopathy model, finding increased RNA polymerase II pausing linked to reduced expression of long neuronal genes.

DOI 10.3389/fnagi.2026.1851916

Drosophilabulk RNA-seq

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