Cancer BiologybioRxivPreprint
Behavioral dysfunction but not wasting in cancer cachexia is driven by altered tryptophan metabolism
Damon Fard, Edisa Pirani, Maria Gomez-Jenkins…·Eileen White
The paper identifies altered tryptophan metabolism in cancer cachexia, showing serotonin depletion and kynurenine accumulation, which drive behavioral dysfunction but not wasting.
DOI 10.64898/2026.10.08.757616