Author

Lucia Puchades Gimeno

Institute of Genetics and CancerORCID 0009-0003-5271-7951Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew A. MalcolmiD· 1 shared Christine J. RodgeriD· 1 shared Duncan SprouliD· 1 shared Francesca Taglini· 1 shared Hazel Davidson‐Smith· 1 shared Ioannis KafetzopoulosiD· 1 shared Moira PasquieriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Andrew A. MalcolmORCID

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1 paper

Recent·Most cited

GenomicsPLoS GeneticsPeer-reviewedApr 2, 2026

DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A

Ioannis Kafetzopoulos, Francesca Taglini, Moira Pasquier…·Duncan Sproul

This study shows that DNMT1 loss causes hypomethylation in late replicating domains but also leads to hypermethylation in some domains due to DNMT3A activity, altering chromatin states.

3 citations

humanDNA methylation

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