Author

Bridget Simonson

Broad InstituteORCID 0009-0003-5601-0953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Mark D. ChaffiniD· 2 shared Patrick T. EllinoriD· 2 shared Abigail S. Mulligan· 1 shared Alex MandiaiD· 1 shared Carla Klattenhoff· 1 shared David A. KassiD· 1 shared Kavita SharmaiD· 1 shared Kenneth B. MarguliesiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

Mark D. ChaffinORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 6, 2025

HeartMap: An Integrated Cell Atlas of 2.4 million cells across 209 Individuals in Health and Disease

Yesh Datar, Mark D. Chaffin, Bridget Simonson…·Patrick T. Ellinor

HeartMap integrates single-nucleus RNA sequencing data from 2.4 million cells across 209 individuals to characterize cardiac cell types and identify disease-associated gene signatures in cardiomyopathies.

1 citation

humanscRNA-seq

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BioinformaticsbioRxivPreprintMar 6, 2025

Single cell transcriptomic analyses of human heart failure with preserved ejection fraction

Virginia Shalkey Hahn, Mark D. Chaffin, Bridget Simonson…·Patrick T. Ellinor

This paper uses snRNA-seq to analyze human HFpEF myocardium, identifying differential gene expression and pathway enrichment in cardiomyocytes and fibroblasts compared to controls and DCM.

12 citations

humansnRNA-seq

𝕏 PostBluesky