Author

Abigail S. Mulligan

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:snRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

David A. KassiD· 2 shared Bridget SimonsoniD· 1 shared Brooke L. LovelandiD· 1 shared Carla Klattenhoff· 1 shared Chi Fung LeeiD· 1 shared Harris E. BlankenshipiD· 1 shared Kavita SharmaiD· 1 shared Keaton E. MinoriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

David A. KassORCID

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2 papers

Recent·Most cited

PFKFB2 Gates a Relationship Between Cardiac Glycolytic Regulation and Electrophysiological Function

Kylene M. Harold, Harris E. Blankenship, Keaton E. Minor, Abigail S. Mulligan, Brooke L. Loveland, Chi Fung Lee, Michael T Kinter, David A. Kass, Stavros Stavrakis, Michael J. Beckstead, Kenneth Michael Humphries

This paper shows that loss of PFKFB2 in cardiac cells leads to electrophysiological instability, including prolonged repolarization and ventricular tachyarrhythmia, linking glycolytic regulation to heart function.

Circulation Arrhythmia and Electrophysiology · Sep 23, 2026Peer-reviewedPhysiology

Single cell transcriptomic analyses of human heart failure with preserved ejection fraction

Virginia Shalkey Hahn, Mark D. Chaffin, Bridget Simonson, Sydney Jenkin, Abigail S. Mulligan, Kenneth C Bedi, Kenneth B. Margulies, Carla Klattenhoff, Kavita Sharma, David A. Kass, Patrick T. Ellinor

This paper uses snRNA-seq to analyze human HFpEF myocardium, identifying differential gene expression and pathway enrichment in cardiomyocytes and fibroblasts compared to controls and DCM.

bioRxiv · Mar 6, 2025 · PreprintBioinformatics