Author

Kiara X Wang

Whitehead Institute for Biomedical ResearchORCID 0009-0003-5927-4188Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

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David P. BarteliD· 1 shared Ryan Yue MulleriD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperMolecular Biology

David P. BartelORCID

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1 paper

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Molecular BiologybioRxivPreprintJun 6, 2026

Dissection of Poly(A)-binding protein (PABPC) cellular function using degron-mediated depletion with replacement

Ryan Yue Muller, Kiara X Wang, David P. Bartel

This paper develops a protein-replacement platform to study PABPC function by degrading endogenous PABPC1/4 and expressing engineered variants, revealing domain-specific roles and functional divergence.

DOI 10.64898/2026.06.05.728833

humanbulk RNA-seq

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