BioinformaticsMolecular Systems BiologyPeer-reviewed
State of the Interactomes: an evaluation of molecular networks for generating biological insights
Sarah N. Wright, Scott Colton, Leah V. Schaffer…·Trey E. Ideker
The paper evaluates 46 human interactomes to identify which are best for disease gene discovery and interaction prediction, finding large networks like HumanNet perform better for disease genes while smaller ones like DIP excel in prediction.
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