BiochemistryScientific ReportsPeer-reviewed
Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3
Alexander J. D. Snow, Tharushi Wijesiriwardena, Benjamin J. Lane…·Alexander L. Breeze
This paper expresses and functionally characterizes the oncogenic RTK FGFR3-TACC3 using cell-free protein expression, achieving significant kinase activity.
2 citations