Author

Hugh Stuart

Dartmouth CollegeORCID 0009-0003-6639-1817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Aaron McKennaiD· 2 shared Abigail C. MarshalliD· 1 shared Fahiima AbdullahiiD· 1 shared Francesco E. EmilianiiD· 1 shared Rachel SaxeiD· 1 shared Zoë Chen· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBioinformatics

Aaron McKennaORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 12, 2025

SCOUT: Ornstein-Uhlenbeck modelling of gene expression evolution on single-cell lineage trees

Hugh Stuart, Aaron McKenna

SCOUT models gene expression evolution on single-cell lineage trees to distinguish neutral drift from selection, validated in C. elegans and lung cancer.

2 citations

C. eleganshuman

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Cancer BiologybioRxivPreprintFeb 27, 2025

Hierarchical Lineage Tracing Reveals Diverse Pathways of AML Treatment Resistance

Rachel Saxe, Hugh Stuart, Abigail C. Marshall…·Aaron McKenna

This study uses FLARE to track AML cell lineage evolution under AraC treatment, revealing resistance mechanisms and validating them in a clinical cohort.

2 citations

mousehuman

𝕏 PostBluesky