Keisuke Hirota

This study benchmarks long-context genome language models on biosynthetic gene clusters, showing layer selection impacts performance and revealing how models encode biological information.

DeepRES identifies candidate proteins for orphan enzymes and discovers novel biosynthetic gene clusters using deep learning.

DeepES identifies orphan enzyme genes using deep learning, focusing on biosynthetic gene clusters and reaction classes, and identifies candidates in metagenome-assembled genomes.