NeurosciencebioRxivPreprint
Inversely proportional myelin growth due to altered Pmp22 gene dosage identifies PI3K/Akt/mTOR signaling as a novel therapeutic target in HNPP
Doris Krauter, David Ewers, Timon J Hartmann…·Michael Werner Sereda
This study identifies PI3K/Akt/mTOR signaling as a therapeutic target for HNPP by showing that mTOR inhibitors reduce hypermyelination in HNPP mouse models.
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