Cancer BiologyNature MetabolismPeer-reviewed
Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production
Kimberly S. Huggler, Kyle M. Flickinger, Matthew H. Forsberg…·Jason R. Cantor
The paper shows that HK2 is essential for cytosolic HK activity and glycolytic ATP production in HPLM, supporting the Warburg effect through compartmentalized ATP synthesis.
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