Author

Kimberly S. Huggler

Morgridge Institute for ResearchORCID 0000-0003-0289-3167Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jason R. CantoriD· 2 shared Aaron D. SimmonsiD· 1 shared Austin K. FeeneyiD· 1 shared Carlos Mellado FritziD· 1 shared Christian M. CapitiniiD· 1 shared Gavin R. ChangiD· 1 shared Kyle M. FlickingeriD· 1 shared Matthew H. ForsbergiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Jason R. CantorORCID

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2 papers

Recent·Most cited

Cancer BiologyNature MetabolismPeer-reviewedJan 16, 2026

Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production

Kimberly S. Huggler, Kyle M. Flickinger, Matthew H. Forsberg…·Jason R. Cantor

The paper shows that HK2 is essential for cytosolic HK activity and glycolytic ATP production in HPLM, supporting the Warburg effect through compartmentalized ATP synthesis.

9 citationstop 1%

humanproteomics

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BioengineeringbioRxivPreprintApr 24, 2025

Human Plasma-Like Medium Promotes Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

Xiaotian Zhange, Aaron D. Simmons, Kimberly S. Huggler…·Sean P. Palecek

This paper shows that Human Plasma-Like Medium (HPLM) improves the maturation of human pluripotent stem cell-derived cardiomyocytes compared to conventional media.

1 citation

humanbulk RNA-seq

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