Author

Guanhua Chen

University of Wisconsin–MadisonORCID 0009-0003-8228-3832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert M. LeviniD· 1 shared Christian Rosas‐SalazariD· 1 shared Meghan H. ShiltsiD· 1 shared Qilin HongiD· 1 shared Suman R Das· 1 shared Tina V. HartertiD· 1 shared Zheng-Zheng TangiD· 1 shared Zhoujingpeng Wei· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Albert M. LevinORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintApr 10, 2026

Fast and reliable association discovery in large-scale microbiome studies and meta-analyses using PALM

Zhoujingpeng Wei, Qilin Hong, Guanhua Chen…·Zheng-Zheng Tang

This paper introduces PALM, a quasi-Poisson regression framework for fast and reliable association discovery in large-scale microbiome studies and meta-analyses, showing improved control of false discovery rates and computational efficiency.

1 citation

metagenomicsstatistical model

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