Tina V. Hartert

This paper introduces PALM, a quasi-Poisson regression framework for fast and reliable association discovery in large-scale microbiome studies and meta-analyses, showing improved control of false discovery rates and computational efficiency.

This study identifies cell type-specific DNA methylation changes in airway epithelial cells linked to early-life RSV infection and their association with subsequent wheezing.

The paper uses single-cell RNA sequencing to study how wheeze and early-life RSV infection affect airway epithelial development in children.

The paper identifies high-value CpGs in the human methylome associated with allergic sensitization using a custom array and WGBS data from airway epithelial cells.

The paper identifies mutations frequent in HRSV vaccine candidates and rare in wild-type genomes that may contribute to vaccine attenuation.

The paper designs a genotyping array (ADPC) for African-specific genetic variation using whole genome sequences from the CAAPA consortium, improving GWAS for African ancestry populations.

This study identifies novel asthma susceptibility loci in individuals of African ancestry through genome-wide association analysis and admixture mapping.